Peripheral Regulation of Microglia-mediated Neuropathology

Microglia are the resident innate immune cells in the brain that serve as central nervous system (CNS) sentinels, quickly detecting and responding to diverse stimuli.  Our research team strives to understand how different environmental exposures and unique peripheral immune responses result in both disease-specific and common mechanisms responsible for microglial driven CNS pathology (Alzheimer’s disease, Parkinson’s disease, and Gulf War Illness), with the goal of understanding how to intervene in these processes.